Karin Lykke-Hartmann Selected Research

familial type 2 Hemiplegic migraine

1/2022	Migraine-Associated Mutation in the Na,K-ATPase Leads to Disturbances in Cardiac Metabolism and Reduced Cardiac Function.
1/2019	Smooth muscle Ca2+ sensitization causes hypercontractility of middle cerebral arteries in mice bearing the familial hemiplegic migraine type 2 associated mutation.
11/2018	Increased susceptibility to cortical spreading depression and epileptiform activity in a mouse model for FHM2.
2/2016	Glutamate-system defects behind psychiatric manifestations in a familial hemiplegic migraine type 2 disease-mutation mouse model.
12/2013	Zebrafish as a novel model to assess Na+/K(+)-ATPase-related neurological disorders.
2/2012	Migraine- and dystonia-related disease-mutations of Na+/K+-ATPases: relevance of behavioral studies in mice to disease symptoms and neurological manifestations in humans.

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Karin Lykke-Hartmann Research Topics

Disease

6	familial type 2 Hemiplegic migraine 01/2022 - 02/2012
5	Dystonia 12 05/2017 - 03/2013
4	Dystonia (Limb Dystonia) 05/2017 - 02/2011
3	Migraine Disorders (Migraine) 01/2022 - 02/2012
3	Alternating hemiplegia of childhood 05/2017 - 01/2016
3	Nervous System Diseases (Neurological Disorders) 01/2016 - 12/2013
2	Migraine with Aura (Familial Hemiplegic Migraine) 01/2022 - 11/2017
2	Ischemia 01/2019 - 01/2017
2	Movement Disorders (Movement Disorder) 05/2017 - 03/2013
2	Spinal Cord Injuries (Spinal Cord Injury) 01/2017 - 01/2017
2	Parkinsonian Disorders (Parkinsonism) 02/2012 - 02/2011
1	Heart Diseases (Heart Disease) 01/2022
1	Heart Failure 01/2022
1	Peripheral Nerve Injuries 01/2019
1	Brain Ischemia (Cerebral Ischemia) 01/2019
1	Hyperalgesia 01/2019
1	Infarction (Infarctions) 01/2019
1	Neuralgia (Stump Neuralgia) 01/2019
1	Pain (Aches) 01/2019
1	Middle Cerebral Artery Infarction (Middle Cerebral Artery Syndrome) 01/2019
1	Stroke (Strokes) 01/2019
1	Epilepsy (Aura) 11/2018
1	Inflammation (Inflammations) 01/2017
1	Neural Tube Defects (Exencephaly) 01/2017
1	Neurodegenerative Diseases (Neurodegenerative Disease) 01/2017
1	Contusions 01/2017
1	CAPOS syndrome 01/2016
1	Hemiplegia (Spastic Hemiplegia) 01/2016
1	Ataxia (Dyssynergia) 01/2016
1	Seizures (Absence Seizure) 01/2016
1	Primary Ovarian Insufficiency 09/2013
1	Folic Acid Deficiency (Folic Acid Deficiencies) 09/2013
1	Spasm (Spasms) 03/2013
1	Neurologic Manifestations (Neurological Manifestations) 02/2012

Drug/Important Bio-Agent (IBA)

13	Adenosine Triphosphatases (ATPase)IBA 01/2022 - 02/2011
10	Protein Isoforms (Isoforms)IBA 01/2022 - 02/2011
2	Glutamic Acid (Glutamate)FDA Link 11/2017 - 02/2016
2	Sodium-Potassium-Exchanging ATPase (Sodium, Potassium ATPase)IBA 05/2017 - 02/2012
2	Folic Acid (Vitamin M)FDA LinkGeneric 01/2017 - 09/2013
2	Ion Pumps (Ion Pump)IBA 01/2017 - 01/2016
1	Mitogen-Activated Protein KinasesIBA 01/2022
1	Malondialdehyde (Propanedial)IBA 01/2022
1	src-Family KinasesIBA 01/2022
1	sortilinIBA 01/2019
1	Tat-NR2B9cIBA 01/2019
1	AntibodiesIBA 01/2019
1	NeurotensinIBA 01/2019
1	N-Methyl-D-Aspartate Receptors (NMDA Receptors)IBA 01/2019
1	N-Methylaspartate (NMDA)IBA 01/2019
1	Neurotensin Receptors (Neurotensin Receptor)IBA 01/2019
1	Brain-Derived Neurotrophic Factor (BDNF)IBA 01/2019
1	UCCB01-144IBA 01/2019
1	Gonadal Steroid Hormones (Sex Hormones)IBA 11/2018
1	Proteins (Proteins, Gene)FDA Link 11/2017
1	Adenosine Triphosphate (ATP)IBA 01/2017
1	Lactic Acid (Lactate)FDA LinkGeneric 01/2017
1	NF-kappa B (NF-kB)IBA 01/2017
1	Nicotine FDA Link 09/2013
1	PotassiumIBA 02/2011
1	SodiumIBA 02/2011

Therapy/Procedure

1	Induced Hypothermia 05/2017